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          目錄:廣州市自力色譜科儀有限公司>>衍生化/食品/藥品等標準品>>OLchem植物生長素>> olchemim Cyclin-dependent kinase inhibitors

          olchemim Cyclin-dependent kinase inhibitors
          • olchemim Cyclin-dependent kinase inhibitors
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          更新時間:2024-06-13 09:18:43瀏覽次數(shù):1086評價

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          olchemim
          Synthetic growth regulators
          CYCLIN-DEPENDENT KINASE INHIBITORS

          Molecules that play key roles in controlling cell-cycle progression are the cyclin-dependent kinase (CDK). Research focused on the primary mechanism of cytokinin action in cell division cycle has showed that natural cytokinins are rather non-specific inhibitors of various kinases. Surprisingly, among cytokinin derivatives, a BAP derivative named olomoucin (OC), which specifically inhibits some CDKs at micromolar concentration.

          OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-9-methylpurine]

          MW 298.35, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 101622-51-9; C15H18N6O
          OLOMOUCINE
          008 021110mg
          008 021220mg
          008 0213100mg
          008 02141mg

          BOHEMINE [6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine]

          MW 340.43, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 1 µM
          S:26, 36; CAS: 189232-42-6; C18H24N6O
          BOHEMINE
          008 07715mg
          008 077210mg
          008 077350mg

          2-HYDROXYBOHEMINE (HOB) [6-(2-hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine]

          MW 356.43, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 0.1 µM
          S:26, 36; CAS: 471270-60-7; C18H24N6O2
          2-HYDROXYBOHEMINE (HOB)
          008 59315mg
          008 593210mg
          008 593350mg

          ISOPROPYL-OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-9-isopropylpurine]

          MW 326.40, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 2 µM
          S:26, 36; CAS: 158982-15-1; C17H22N6O
          ISOPROPYL-OLOMOUCINE
          008 07815mg
          008 078210mg
          008 078350mg

          ISO-OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-7-methylpurine]

          MW 298.35, crystalline, purity > 98% (HPLC)
          Inactive 7-isomer of olomoucine.
          IC50 value for CDK1: 200 µM
          S:26, 36; CAS: 101622-50-8; C15H18N6O
          ISO-OLOMOUCINE
          008 07915mg
          008 079210mg
          008 079350mg

          OLOMOUCINE II [6-(2-hydroxybenzylamino)-2(R)-[1-(hydroxymethyl)propyl]amino-9-isopropylpurine]

          MW 370.46, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 0.02 µM
          S:26, 36; CAS: 500735-47-7; C19H26N6O2
          OLOMOUCINE II
          008 52615mg
          008 526210mg
          008 526350mg

          RS-ROSCOVITINE [6-benzylamino-[2-(1(RS)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

          MW 354.45, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 0.45 µM
          S:26, 36; CAS: 186692-44-4; C19H26N6O
          RS-ROSCOVITINE
          008 03615mg
          008 036210mg
          008 036350mg

          R-ROSCOVITINE 6-benzylamino-2-[1(R)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

          MW 354.45, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 0.2 µM
          S:26, 36; CAS: 186692-46-6; C19H26N6O
          R-ROSCOVITINE
          008 57415mg
          008 574210mg
          008 574350mg

          S-ROSCOVITINE [6-benzylamino-2-[1(S)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

          MW 354.45, crystalline, purity > 98% (HPLC)
          IC50 value for CDK1: 0.6 µM
          S:26, 36; CAS: 186692-45-5; C19H26N6O
          S-ROSCOVITINE
          008 57515mg
          008 575210mg
          008 575350mg

          PURVALANOL A [6-(3-chlorophenyl)amino-2-[1(R)-(hydroxymethyl)-2-(methyl)propyl]amino-9-isopropylpurine]

          MW 388.90, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 212844-53-6; C19H25ClN6O
          PURVALANOL A
          008 08515mg
          008 085210mg
          008 085350mg

          AMINOPURVALANOL (APURV) [(R)-2-[6-(3-amino-5-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino]-3-methyl-butan-1-ol]

          MW 403.91, crystalline, purity > 98% (HPLC)
          R:22, S:22, 24/25; CAS: 220792-57-4; C19H26ClN7O
          AMINOPURVALANOL (APURV)
          008 59515mg
          008 595210mg
          008 595325mg

          MYOSEVERIN [9-isopropyl-2,6-bis(4-methoxybenzylamino)purine]

          MW 432.53, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 267402-71-1; C24H28N6O2
          MYOSEVERIN
          008 08615mg
          008 086210mg
          008 086350mg

          2-CHLORO-6-BENZYLAMINO-9-ISOPROPYLPURINE

          MW 301.78, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 186692-41-1; C15H16ClN5
          2-CHLORO-6-BENZYLAMINO-9-ISOPROPYLPURINE
          008 527150mg
          008 5272100mg
          008 5273250mg
          008 52741g

          2-CHLORO-6-BENZYLAMINO-7-METHYLPURINE

          MW 273.73, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 101622-52-0; C13H12ClN5
          2-CHLORO-6-BENZYLAMINO-7-METHYLPURINE
          008 528110mg
          008 528250mg
          008 5283100mg

          2-CHLORO-6-BENZYLAMINO-9-METHYLPURINE

          MW 273.73, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 101622-53-1; C13H12ClN5
          2-CHLORO-6-BENZYLAMINO-9-METHYLPURINE
          008 529150mg
          008 5292100mg
          008 5293250mg
          008 52941g

          2-CHLORO-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE

          MW 251.72, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 189232-32-4; C11H14ClN5
          2-CHLORO-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE
          008 530150mg
          008 5302100mg
          008 5303250mg
          008 53041g

          CVT 313

          MW 400.48, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 199986-75-9; C20H28N6O3
          CVT 313
          008 57615mg
          008 576210mg
          008 576350mg

          NG 38 [2-(1-piperenidinyl)-6-(3-nethoxybenzylamino)-9-isopropylpurine]

          MW 380.50, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: NONE; C21H28N6O
          NG 38
          008 59115mg
          008 591210mg
          008 591350mg

          2-(2-HYDROXYETHYLAMINO)-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE

          MW 276.34, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 158982-16-2; C13H20N6O
          2-(2-HYDROXYETHYLAMINO)-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE
          008 53115mg
          008 531210mg
          008 531350mg

          INDIRUBIN [3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one]

          MW 260.27, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 479-41-4; C16H10N2O2
          IC50 value for CDK1: 10 µM
          INDIRUBIN
          008 58315mg
          008 583210mg
          008 583350mg

          INDIRUBIN-5’-SULPHONIC ACID [3,2'-dioxo-1,3,1',2'-tetrahydro-[2,3']biindolylidene-5'-sulfonic acid]

          MW 342.33, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 864131-82-8; C16H10N2O5S
          IC50 value for CDK1: 0.055 µM
          INDIRUBIN-5’-SULPHONIC ACID
          008 58415mg
          008 584210mg
          008 584350mg

          INDIRUBIN-3’-MONOOXIME [1H,1'H-[2,3']bisindolylidene-3,2'-dione 3-oxime]

          MW 277.28, crystalline, purity > 98% (HPLC)
          S:26, 36; CAS: 160807-49-8; C16H11N3O2
          IC50 value for CDK1: 0.18 µM
          INDIRUBIN-3’-MONOOXIME
          008 58515mg
          008 585210mg
          008 585350mg

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