流體剪切力系統(tǒng)
美國flexcell str-4000細(xì)胞流體剪切應(yīng)力加載培養(yǎng)系統(tǒng)介紹:
●為細(xì)胞提供各種形式的流體切應(yīng)力:穩(wěn)流式、脈沖式、往返式震蕩式剪切切應(yīng)力。
●在經(jīng)過特殊基質(zhì)蛋白包被細(xì)胞培養(yǎng)載片上培養(yǎng)細(xì)胞:
Streamer載片規(guī)格:25mm x 75mm x 1.0mm
Flexflow蓋片規(guī)格:25mm x 75mm x 0.2mm
●計算機(jī)控制的蠕動泵可以調(diào)節(jié)切應(yīng)力的大小,從0-35 dynes/cm2
●Osci-Flow液體控制儀提供往返式或者脈沖式的流體切應(yīng)力。
●檢測細(xì)胞在液流作用下的排列反應(yīng)。
●設(shè)備易拆卸并可高溫消毒。
●streamer多達(dá)6通道,每個通道放不同載片,可培養(yǎng)不同的細(xì)胞
●FlexFlow提供流體切應(yīng)力同時抻拉細(xì)胞,并可在顯微鏡下進(jìn)行實時觀察
flexcell str-4000細(xì)胞流體剪切應(yīng)力加載培養(yǎng)系統(tǒng)應(yīng)用文獻(xiàn):
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美國Flexcell公司,成立于1987年,該公司專注于細(xì)胞力學(xué)培養(yǎng)產(chǎn)品的設(shè)計和制造。以提供*的體外細(xì)胞拉應(yīng)力、壓應(yīng)力和流體剪切應(yīng)力加載刺激系統(tǒng)以及配套的培養(yǎng)板、硅膠膜載片等耗材*。
Flexcell細(xì)胞組織力學(xué)培養(yǎng)系統(tǒng)不僅能對各種2D、3D細(xì)胞組織提供拉應(yīng)力、壓應(yīng)力、切應(yīng)力刺激加載,而且還可以提供拉應(yīng)力和切應(yīng)力混合力同時加載;不僅能對細(xì)胞組織進(jìn)行機(jī)械力加載刺激,而且還能進(jìn)行三維培養(yǎng)、人工生物組織構(gòu)建、動力模擬;不僅能單軸向牽張拉伸,而且還可以雙軸向牽張拉伸;不僅可以根據(jù)實驗需要調(diào)節(jié)受力大小,而且還可以模擬不同受力時間。
Flexcell*的StageFlexer拉應(yīng)力顯微設(shè)備、StagePresser壓應(yīng)力顯微設(shè)備、Flex Flow切應(yīng)力顯微設(shè)備,可在加力培養(yǎng)的同時實時觀察研究細(xì)胞組織在力作用下的反應(yīng)變化;*的flexstop隔離閥能使同一塊培養(yǎng)板里的細(xì)胞組織一部分受力,一部分不受力,方便進(jìn)行對比實驗
這些系統(tǒng)智能、精準(zhǔn)誘導(dǎo)來自各種細(xì)胞、組織在拉應(yīng)力、壓應(yīng)力和流體切應(yīng)力作用下發(fā)生的生化生理變化,專業(yè)、細(xì)膩的闡釋了體外細(xì)胞、組織機(jī)械力刺激加載、力學(xué)信號感受和響應(yīng)機(jī)制。對研究細(xì)胞的形態(tài)結(jié)構(gòu)及功能,細(xì)胞的生長、發(fā)育、成熟、增殖、衰老、凋亡、死亡及癌變以及通路表達(dá),細(xì)胞信號傳導(dǎo)及基因表達(dá)的調(diào)控,細(xì)胞的分化及其調(diào)控機(jī)理具有重要意義。