皮膚（傷口愈合）SKIN (WOUND HEALING)

皮膚（傷口愈合）SKIN (WOUND HEALING)

創(chuàng)傷愈合是創(chuàng)傷后組織自我修復(fù)的過(guò)程。在皮膚傷口愈合的背景下，目標(biāo)是以恢復(fù)原始功能和結(jié)構(gòu)特性的方式再生組織，同時(shí)盡量減少疤痕的出現(xiàn)。傷口愈合研究在臨床前階段特別有用，以驗(yàn)證特定藥物對(duì)自然愈合能力沒(méi)有負(fù)面影響。評(píng)價(jià)創(chuàng)傷過(guò)程質(zhì)量的一個(gè)簡(jiǎn)單方法是評(píng)價(jià)創(chuàng)傷破裂時(shí)的張力負(fù)荷。旨在改善傷口愈合效果的產(chǎn)品需要展示它們?cè)诨謴?fù)皮膚機(jī)械功能方面的表現(xiàn)。

Wound healing is the process by which a tissue repairs itself after trauma. In the context of wound healing of skin, the goal is to regenerate the tissue in a manner that the original functional and structural properties are restored, while minimizing the appearance of the scar. Wound healing studies are particularly useful in the preclinical phase to verify that a particular drug has no negative effect on natural healing capabilities. A straightforward way to evaluate the quality of the wounding process is to evaluate the tension load at rupture of the wound. Products designed to improve the outcome of wound healing need to demonstrate how they perform in restoring the mechanical function of the skin.