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          • Liver-Chip肝臟芯片現(xiàn)貨, Emulate, Inc

          • Liver-Chip肝臟芯片現(xiàn)貨, Emulate, Inc

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          • 型號(hào) LIVER BIO-KIT
          • 品牌
          • 廠商性質(zhì) 代理商
          • 所在地 北京市

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          更新時(shí)間:2020-01-23 16:30:30瀏覽次數(shù):1415

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          應(yīng)用領(lǐng)域 醫(yī)療衛(wèi)生,生物產(chǎn)業(yè)    
          Liver-Chip肝臟芯片現(xiàn)貨, Emulate, Inc, LIVER BIO-KIT

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          Liver-Chip肝臟芯片現(xiàn)貨, Emulate, Inc, LIVER BIO-KIT

          授權(quán)代理,現(xiàn)貨供應(yīng),

          Model Overview

          Our Liver-Chip recreates true-to-life functions of the liver and is available in three different cell configurations: co-culture, tri-culture, and quad-culture. Our human Liver-Chip incorporates relevant extracellular matrix (ECM) interactions, a hepatocyte and liver sinusoidal endothelial cell interface, along with relevant cyto-architecture, and physiological flow.

          Liver-Chip Diagram.png

          Liver-Chip_Hepatocytes.jpg

          Liver-Chip_Kupffer-Cell.jpeg

          Bright-Field Image of Liver-Chip

          MRP2 Staining of Liver-Chip

          Configurations

          Our Human Liver-Chip can be set up into various configurations using our approved protocols, depending on study requirements — including co-, tri-, and quad-culture.

          co-culture copy.jpg

          Co-Culture

          hepatocytes + LSECs

          tri-culture copy.jpg

          Tri-Culture

          Co-Culture + Kupffer cells

          quad-culture copy.jpg

          Quad-Culture

          Tri-Culture + stellate cells

          Applications


          Our Liver-Chip demonstrates in vivo-relevant responses to known and tool compounds at clinically relevant concentrations and through the appropriate mechanisms of action.

          General Toxicity · Mechanistic Toxicity · Nutrient Metabolism

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          LIVER BIO-KIT

          Our Human Liver-Chip is currently available as a complete kit including Organ-Chips, cells, reagents, training, and support from our team of experts. For more information about kit options and pricing, contact us below.

           

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          LIVER SERVICES

          We offer services run on our Liver-Chips to deliver clinically-relevant, decision-worthy insights. Our experienced services team is ready to design and execute studies with your desired endpoints in mind.

           

          Resources

           

          PUBLICATIONS

          Reproducing Human and Cross-Species Drug Toxicities Using a Liver-Chip

          Nonclinical rodent and nonrodent toxicity models used to support clinical trials of candidate drugs may produce discordant results or fail to predict complications in humans, contributing to drug failures in the clinic. Here, we applied microengineered Organs-on-Chips technology to design a rat, dog, and human Liver-Chip….

          Nov 6, 2019

          PROTOCOLS

          Protocols developed by our experts guide the process of Liver-Chip culture and analysis.

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