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產(chǎn)品簡介

Cerebro Flow Loop system血管研究儀器系統(tǒng),腦血管流量回路模擬系統(tǒng)
Vascular Simulations Replicator （patent #9,183,763 B2）：*個復(fù)制心動周期和血流的系統(tǒng)（The first system that replicates cardiac cycle and blood flow）血管模擬復(fù)制（＃9183763 B2）

詳細(xì)介紹

Vascular Simulations Replicator,血管模擬復(fù)制儀器裝置

血管模擬復(fù)制（＃9183763 B2）復(fù)制與官能左心房和心室的機(jī)械二尖瓣和主動脈瓣的心動周期。然后，“血液流動”通過重新產(chǎn)生臨床Windkessel效應(yīng)的依從性的硅氧烷主動脈，導(dǎo)致復(fù)制器的主動脈中與人主動脈的波形不可區(qū)分的壓力波形。從主動脈弓和腦血管系統(tǒng)產(chǎn)生的巨大血管可以從實(shí)際患者的成像研究中得到原型，并且其整個血管解剖結(jié)構(gòu)和病理學(xué)可以用硅樹脂重建。目前，可以重建任何顱內(nèi)動脈瘤。正在開發(fā)的其他模塊包括顱內(nèi)閉塞以模擬急性中風(fēng)，頸動脈狹窄，顱內(nèi)動靜脈畸形，腹主動脈瘤和主動脈和二尖瓣狹窄。

具有與人血液粘度相匹配的專有清除血液類似物在穿過血管系統(tǒng)時復(fù)制血管內(nèi)裝置，電線和導(dǎo)管的摩擦系數(shù)。血液模擬液體被自動加熱至體溫（98.6°F）復(fù)制。此外，腦血管系統(tǒng)被容納在充滿凝膠的聚氨酯“頭部”中，該凝膠模擬腦實(shí)質(zhì)的順應(yīng)性。因此，電線和導(dǎo)管進(jìn)入腦血管系統(tǒng)模擬血管的矯正，如臨床可視化。Replicator配有Windows筆記本電腦，預(yù)裝的軟件應(yīng)用程序通過藍(lán)牙連接操作Replicator。軟件功能包括填充，運(yùn)行和排水Replicator，以及控制以改變心率和平均血流速率到頭部和身體。下圖顯示了Replicator在不同動脈位置記錄的流量波形。
整個系統(tǒng)可以放置在任何熒光檢查環(huán)境中，并且可以在包括雙平面血管造影系統(tǒng)的任何機(jī)器中執(zhí)行成像。可以使用任何造影劑進(jìn)行標(biāo)準(zhǔn)熒光透視，路線圖成像，數(shù)字減影血管造影和旋轉(zhuǎn)血管造影，并且可以獲得與真實(shí)臨床病例相同的獲取序列。正在開發(fā)“人造腎”系統(tǒng)來消除循環(huán)系統(tǒng)的對比。
相同的解剖學(xué)和病理學(xué)
與基本上是美化的視頻游戲的虛擬模擬器不同，血管模擬復(fù)制器在執(zhí)行血管內(nèi)手術(shù)時提供了一個現(xiàn)實(shí)的體驗(yàn)。用戶界面是與用于執(zhí)行實(shí)際臨床情況的任何血管內(nèi)進(jìn)入產(chǎn)品或裝置組合的血管造影環(huán)境。此外，可以制造復(fù)制實(shí)際解剖和病理學(xué)的定制硅膠容器。干預(yù)主義者*能夠采用相同的血管病理學(xué)方法進(jìn)行臨床治療。

Cerebrovascular Flow Loop

case1

Our cerebrovascular flow loop consists of a plexiglass box which fits all of our intracranial vessels. Included in the unit are: one fluid storage container, one hemostasis valve Y-connector with touhy-borst adapter, and one perastaltic pump. This is a compact, easy-to-use setup for training and device evaluation with our Intracranial Vessels

The Replicator

The Vascular Simulations Replicator (patent #9,183,763 B2) duplicates the cardiac cycle with a functional left atrium and ventricle with mechanical mitral and aortic valves. The “blood flow” then passes through a silicone aorta with a compliance that recreates the clinical Windkessel effect resulting in pressure waveforms in the aorta of the replicator that are indistinguishable from the waveforms of a human aorta. The great vessels arising from the aortic arch and the cerebrovasculature can be prototyped from imaging studies of actual patients and their entire vascular anatomy and pathology can be recreated with silicone. Currently, any intracranial aneurysm can be recreated. Additional modules under development include intracranial occlusion to mimic acute stroke, carotid stenosis, intracranial arteriovenous malformations, abdominal aortic aneurysms and aortic and mitral stenosis.

replicator

A proprietary clear blood analog with a viscosity matching that of human blood duplicates the friction coefficients of endovascular devices, wires, and catheters as they traverse the vascular system.The blood analog fluid is automatically warmed up to body temperature(98.6 °F) by the Replicator. In addition, the cerebrovasculature is housed in a polyurethane “head” filled with a gel that mimics the compliance of the brain parenchyma. As a result, the passage of wires and catheters into the cerebrovasculature mimics the straightening of vessels as visualized clinically.The Replicator comes with a Windows laptop with a pre-installed software application that operates the Replicator via Bluetooth connectivity. Software functions include filling, running, and draining the Replicator, as well as controls to change the heart rate and mean blood flow rates to the Head and Body. The plots below show the flow waveforms recorded on the Replicator at different arterial sites.

The whole system can be placed in any fluoroscopic environment and imaging can be performed in any machine including biplane angiography systems. Standard fluoroscopy, roadmap imaging, digital subtraction angiography and rotational angiography can be performed with any contrast agent and acquisition sequences identical to real clinical cases can be obtained. “Artificial kidney” systems to remove contrast from the circulatory system are under development.

Identical Anatomy and Pathology

Unlike virtual simulators which are essentially glorified video games, the Vascular Simulations Replicator provides a realistic experience when performing endovascular procedures. The user interface is the angiographic environment in combination with any endovascular access product or device utilized to perform an actual clinical case. In addition, custom silicone vessels that duplicate the actual anatomy and pathology can be manufactured. For the first time, interventionalists will be able to practice a procedure with the identical vascular pathology they will ultimay treat clinically.

Vessels Catalog

Vascular Simulations can create custom silicone vessels from the AXIAL SLICES reconstructed from a 3D rotational angiogram, CT angiogram, or MR angiogram of any patient's vasculature. Please select any of the ‘off-the-shelf’ vessels shown below or Upload your patient dataset and let us know. You can also send us your CAD or STL files instead of imaging datasets. Please note that the vessels are filled with red colored fluid for visualization. Any vessel in the catalog can be mirrored.