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        1. 翌圣生物科技(上海)股份有限公司

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          400-6111-883

          您現(xiàn)在的位置: 翌圣生物科技(上海)股份有限公司>>細胞生物學>>細胞因子>> 92516ESRecombinant Human Epiregulin
          92516ESRecombinant Human Epiregulin
          參考價385
          具體成交價以合同協(xié)議為準
          • 92516ES 型號
          • Yeasen/翌圣生物 品牌
          • 生產商 廠商性質
          • 上海市 所在地

          規(guī)格
          5 μg385元99 件 可售

          訪問次數(shù):129更新時間:2024-05-06 08:57:02

          聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息,謝謝!
          初級會員·12年
          聯(lián)人:
          曹女士
          話:
          400-6111-883
          機:
          后:
          4006-111-883
          真:
          86-21-34615995
          址:
          上海市浦東新區(qū)天雄路166弄1號3樓
          網(wǎng)址:
          www.yeasen.com

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          產品簡介
          供貨周期 現(xiàn)貨 應用領域 醫(yī)療衛(wèi)生,生物產業(yè)
          Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as
          產品介紹

          Product Information

          Product  Name

          Cat#

          Size

          Recombinant Human Epiregulin Protein

          92516ES08

          5μg

          92516ES50

          5μg

          92516ES60

          100μg

          92516ES76

          500μg

           

          Product Description

          Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

           

          Product Properties

          Synonyms

          EREG

          Accession

          O14944 

          GeneID

          2069

          Source

          E.coli-derived Human Epiregulin protein,Val60-Leu108.

          Molecular Weight

          Approximately 5.6 kDa.

          AA Sequence

          AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

          Tag

          None

          Physical Appearance

          Sterile Filtered White lyophilized (freeze-dried) powder.

          Purity

          > 97 % by SDS-PAGE and HPLC analyses.

          Biological Activity

          Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 × 105 IU/mg.

          Endotoxin

          < 1.0 EU per 1μg of the protein by the LAL method.

          Formulation

          Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

          Reconstitution

          We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

           

          Shipping and Storage

          The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

          Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

           

          Cautions

          1. Avoid repeated freeze-thaw cycles.

          2. For your safety and health, please wear lab coats and disposable gloves for operation.

          3. For research use only.





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