Dextran sulfate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid.
Dextran sulfate sodium salt葡聚糖硫酸鈉鹽 MW:40000
Description（描述）
Dextran sulfate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. The sulfur content is approximay 17% which corresponds to an average of 1.9 sulfate groups per glucosyl residue of the dextran molecule.
Typical Uses（典型用途）
Increases hybridization rate of nucleic acids - in the presence of 10% dextran sulfate the rate of reannealing of DNA in solution was increased by about 10 times. This observation was later extended to the hybridization of single or double-stranded probes to DNA or RNA immobilized on filter paper. The addition of 10% dextran sulfate may increase the rate of hybridization of randomly cleaved double-stranded DNA probes to immobilized nucleic acids by as much as 100 times.
Shows immunologically relevant activities:
1.enhancement and suppression of humoral immunity
2.polyclonal activation of B-lymphocytes, stimulating even immature B cells
3.changes in thymocyte reactivity to lectins
4.inhibition of blood coagulation and plaet aggregation
5.enhancement of blood fibrinolytic activity
6.enhancement/suppression of cell-mediated immune responses.
Precipitates LDL and VLDL lipoproteins - in the presence of magnesium ions, dextran sulfate precipitates low-density lipoproteins from human serum leaving the high-density lipoproteins in the supernatant. Removal of lipoproteins by dextran sulfate precipitation may be useful in the purification of other materials such as beta2-glycoprotein.
Shows activity as an adjuvant
Structure（結構式）:
CAS # : 9011-18-1
Physical Description（外觀）: White to off-white powderSolubility（溶解性）: Soluble in water （100 mg/ml - clear to slightly hazy yellow solution. Higher molecular weight products may not be as soluble in water as the lower molecular weight products.）. Aqueous solutions should be buffered with （e.g. with sodium bicarbonate） before autoclaving to prevent decomposition.
Ordering information（訂購信息）
| 貨號 | 名稱 | 產地 | 規(guī)格 | 報價/元 |
| 60316ES25 | Dextran sulfate sodium salt葡聚糖硫酸鈉鹽 MW:40000 | YEASEN | 25g | 232 |
| 60316ES60 | Dextran sulfate sodium salt葡聚糖硫酸鈉鹽 MW:40000 | YEASEN | 100g | 704 |
初級會員·12年
