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        1. 上海信裕生物科技有限公司
          中級會員 | 第11年

          15221858802

          當(dāng)前位置:上海信裕生物科技有限公司>>重組蛋白>>人重組蛋白>> 早幼粒細(xì)胞白血病蛋白(PML)重組蛋白

          早幼粒細(xì)胞白血病蛋白(PML)重組蛋白

          參  考  價:1800 - 2880
          具體成交價以合同協(xié)議為準(zhǔn)
          • 型號

          • 品牌

            上海信裕生物科技有限公司

          • 廠商性質(zhì)

            生產(chǎn)商

          • 所在地

            上海市

          規(guī)格

          50µg 1800元 99瓶可售

          100µg 2880元 99瓶可售

          更新時間:2024-11-25 19:39:54瀏覽次數(shù):12次

          聯(lián)系我時,請告知來自 化工儀器網(wǎng)
          CAS 詳見說明書 純度 > 97%
          分子量 27.2kDa 分子式 詳見說明書
          供貨周期 一周 規(guī)格 50μg/100μg
          貨號 XY94039RPHu 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
          主要用途 SDS-PAGE; WB
          PML抗原;早幼粒細(xì)胞白血病蛋白(PML)重組蛋白多種屬 該基因編碼的蛋白質(zhì)是三重基序(TRIM)家族的成員。TRIM基序包括三個鋅結(jié)合結(jié)構(gòu)域,一個RING、一個B-box型1和一個B-box型2,以及一個線圈區(qū)域。這種磷蛋白定位于核小體,在那里它作為轉(zhuǎn)錄因子和腫瘤抑制因子發(fā)揮作用。其表達(dá)與細(xì)胞周期有關(guān),并調(diào)節(jié)p53對致癌信號的反應(yīng)。該基因通常與急性早幼粒細(xì)胞白血?。ˋPL)相關(guān)的視黃酸受體α基因

          Recombinant Promyelocytic Leukemia Protein (PML) 

          早幼粒細(xì)胞白血病蛋白(PML)重組蛋白

          [ PROPERTIES ]

          Source: Prokaryotic expression

          Host: E.coli

          Residues:  Gln59~Glu239

          Tags:  N-terminal His Tag

          Subcellular Location: Nucleus, Cytoplasm

          Purity: > 97%

          Traits: Freeze-dried powder

          Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose.

          Original Concentration: 150µg/mL

          Applications: Positive Control; Immunogen; SDS-PAGE; WB.

          (May be suitable for use in other assays to be determined by the end user.)

          Predicted isoelectric point: 5.9

          Predicted Molecular Mass:  27.2kDa

          Accurate Molecular Mass:  31kDa as determined by SDS-PAGE reducing conditions.

          Phenomenon explanation:

          The possible reasons that the actual band size differs from the predicted are as follows:

          1.Splice variants: Alternative splicing may create different sized proteins from the same gene.

          2. Relative charge: The composition of amino acids may affects the charge of the protein.

          3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.

          4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form.

          5. Polymerization of the target protein: Dimerization, multimerization etc.

          [ USAGE ]

          Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

          [ STORAGE AND STABILITY ]

          Storage: Avoid repeated freeze/thaw cycles.

                       Store at 2-8oC for one month.

                       Aliquot and store at -80oC for 12 months.

          Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

          [SEQUENCE ]

          早幼粒細(xì)胞白血病蛋白(PML)重組蛋白

          [  IDENTIFICATION  ]

          早幼粒細(xì)胞白血病蛋白(PML)重組蛋白

          [ IMPORTANT NOTE ]

          The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.

          特別提示:本公司的所有產(chǎn)品僅可用于科研實驗,嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!以實際收貨產(chǎn)品說明書為準(zhǔn),網(wǎng)站說明書僅供參考!









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