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當(dāng)前位置:深圳欣博盛生物科技有限公司>>蛋白&肽>> α2-Macroglobulin (human plasma), (purified)
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品 牌Enzo Life Sciences
廠商性質(zhì)代理商
所 在 地深圳市
更新時間:2022-01-28 14:25:30瀏覽次數(shù):639次
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DNER (extracellular domain) (human)
供貨周期 | 兩周 | 規(guī)格 | 1*1mg |
---|---|---|---|
貨號 | BML-SE502-0001 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
主要用途 | 科研 |
α2-Macroglobulin (human plasma), (purified)
MW: | 725 kDa |
Source: | Isolated from human plasma that is tested to be negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2. |
UniProt ID: | P01023 |
Shipping: | Shipped on Blue Ice |
Long Term Storage: | -20°C |
Scientific Background: | In addition to binding TGF-β and β-amyloid, α2-macroglobulin covalently binds and inhibits a wide range of proteases, including ADAMs, calpains, cathepsins, chymase, clotting factors, kallikreins, MMPs, neutrophil elastase, and proteinase 3. It also plays a role in the innate immune system, inhibiting parasitic proteases. When treated with methylamine, it blocks binding of apoE to lipoprotein receptor-related protein (LRP). |
Regulatory Status: | RUO - Research Use Only |
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