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Source

Rabbit

Applications

WB, ELISA

Reactivity

Human, Mouse, Rat

Dilution

WB 1:500-2000, ELISA(peptide)1:5000-20000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)

Uniprot No

Q9UQM7/Q13557

Alternative names

Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

calcium/calmodulin dependent protein kinase II alpha(CAMK2A) Homo sapiens The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

Other

CAMK2D CAMKD, CaMK2 (Phospho-Thr286)

Concentration

1 mg/ml