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          目錄:上海貝博生物科技有限公司>>Primary Antibodies>> 11β-HSD1 rabbit pAb

          11β-HSD1 rabbit pAb
          • 11β-HSD1 rabbit pAb
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          SourceRabbitApplicationsWB,IHC,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000
          • Source

            Rabbit

          • Applications

            WB,IHC,ELISA

          • Reactivity

            Human,Mouse,Rat

          • Dilution

            WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

          • Storage

            -20°C/1 year

          • Specificity

            11β-HSD1 Polyclonal Antibody detects endogenous levels of 11β-HSD1 protein.

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            The antiserum was produced against synthesized peptide derived from human HSD11B1. AA range:1-50

          • Uniprot No

            P28845

          • Alternative names

            HSD11B1; HSD11; HSD11L; Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1

          • Form

            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011],

          • Other

            HSD11B1, Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-beta-hydroxysteroid dehydrogenase 1

          • Mol.Wt (Da)

            32401

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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