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Source

Rabbit

Applications

IHC,IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

ACTR-IC Polyclonal Antibody detects endogenous levels of ACTR-IC protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250

Uniprot No

Q8NER5

Alternative names

ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

activin A receptor type 1C(ACVR1C) Homo sapiens ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligａnd binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008],

Other

ACVR1C, Activin receptor type-1C;Activin receptor-like kinase 7; ALK-7

Mol.Wt (Da)

54871

Concentration

1 mg/ml