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          目錄:上海貝博生物科技有限公司>>Primary Antibodies>> Actinin-α2/3 rabbit pAb

          Actinin-α2/3 rabbit pAb
          • Actinin-α2/3 rabbit pAb
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          SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000
          • Source

            Rabbit

          • Applications

            WB,IHC,IF,ELISA

          • Reactivity

            Human,Mouse,Rat

          • Dilution

            WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

          • Storage

            -20°C/1 year

          • Specificity

            Actinin-α2/3 Polyclonal Antibody detects endogenous levels of Actinin-α2/3 protein.

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            The antiserum was produced against synthesized peptide derived from human Actinin alpha-2/3. AA range:31-80

          • Uniprot No

            P35609/Q08043

          • Alternative names

            ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein

          • Form

            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            actinin alpha 2(ACTN2) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],

          • Other

            ACTN2/ACTN3, Alpha-actinin-2/3, F-actin cross-linking protein; ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein

          • Mol.Wt (Da)

            103854

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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