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          目錄:上海貝博生物科技有限公司>>Primary Antibodies>> Active Caspase-3 mouse mAb(5E1)

          Active Caspase-3 mouse mAb(5E1)
          • Active Caspase-3 mouse mAb(5E1)
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          SourceMouseApplicationsIF
          • Source

            Mouse

          • Applications

            IF,WB,IHC

          • Reactivity

            Human,Mouse,Rat,Chicken

          • Dilution

            IF: 1:50-200 WB: 1:500-1000 IHC: 1:100-200

          • Storage

            -20°C/1 year

          • Specificity

            The antibody detects endogenous Active Caspase-3 protein.

          • Source/Purification

            The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            Recombinant Protein of Active Caspase-3

          • Uniprot No

            P42574

          • Alternative names

            CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1

          • Form

            PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

          • Clonality

            Monoclonal

          • Isotype

            IgG

          • Background

            caspase 3(CASP3) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer&apos;s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],

          • Other

            CASP3, Caspase-3; Protein Yama; SREBP cleavage activity 1; SCA-1

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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