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          目錄:上海貝博生物科技有限公司>>Primary Antibodies>> Actinin-α1 rabbit pAb2

          Actinin-α1 rabbit pAb2
          • Actinin-α1 rabbit pAb2
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          SourceRabbitApplicationsWB
          • Source

            Rabbit

          • Applications

            WB,IHC

          • Reactivity

            Mouse,Rat

          • Dilution

            WB: 1:1000-2000 IHC: 1:200-500

          • Storage

            -20°C/1 year

          • Specificity

            The antibody detects endogenous Actinin-α1 protein.

          • Source/Purification

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

          • Immunogen

            Recombinant Protein of Actinin-α1

          • Uniprot No

            P12814

          • Alternative names

            ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1

          • Form

            PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

          • Clonality

            Polyclonal

          • Isotype

            IgG

          • Background

            actinin alpha 1(ACTN1) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

          • Other

            ACTN1, Alpha-actinin-1

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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