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          陜西新研博美生物科技有限公司>技術(shù)文章>蛋白點(diǎn)擊試劑DBCO-NHS功能簡(jiǎn)介

          技術(shù)文章

          蛋白點(diǎn)擊試劑DBCO-NHS功能簡(jiǎn)介

          閱讀:769          發(fā)布時(shí)間:2018-7-24

          中文名稱:DBCO-NHS

          英文名稱:Dibenzocyclooctyne-N-hydroxysuccinimidyl ester

          英文別名:Dibenzocyclooctyne-N-hydroxysuccinimidyl ester;

          2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;

          DBCO-NHS ester;2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;DBCO-succinyl N-hydroxysuccinimidyl ester;

          CAS號(hào):1353016-71-3

          分子式:C23H18N2O5

          分子量:402.39900

          質(zhì)量:402.12200

          PSA:83.99000

          LogP:2.32330

          結(jié)構(gòu)式:


          Description:
          DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction.  This reaction has excellent selectivity and biocompatibility, such that the complimentary reagents can form covalent bonds with richly functionalized biological systems. The Cu-free click reaction has been a powerful tool in catalyst-free bioconjugation. DBCO reagents posses fast kinetcs and stability in aqueous buffer and they can be used to label azide-modified biomolecules with high specificity and reactivity. 

          Physical Properties:
          Yellow/pale-yellow solid or viscous liquid;
          Soluble in DMSO or DMF;
          Storage Conditions:
          Store at -20 0C, desiccate. NHS tends to hydrolyze from moisture. Avoid frequent thaw and frozen.

           

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          TCO-Tetrazine Ligation Chemistry產(chǎn)品列表:
          TCO-PEG4-NHS ester
          UV-Tracer TCO-NHS ester
          TCO-NHS ester
          TCO-PEG3-Maleimide
          TCO-Amine HCl salt
          TCO-PEG12-DBCO
          Tetrazine-PEG5-NHS ester
          Tetrazine-PEG4-Maleimide
          Tetrazine-PEG4-Alkyne
          Tetrazine-DBCO
          Tetrazine-PEG4-Azide
          Tetrazine – Fluorescent Dye Conjuagtes
          Copper-catalyzed Click Chemistry產(chǎn)品列表:
          Alkyne-PEG4-NHS ester
          Propargyl-NHS ester
          Alkyne-PEG4-Acid
          Alkyne-PEG4-Amine
          Alkyne-PEG4-Maleimide
          Propargyl-Maleimide
          Fluorescent Alkynes
          Biotin-PEG4-Alkyne
          Diazo Biotin-Alkyne
          Fluorescent Azides
          Azido-PEG4-NHS ester
          Azidoacetic acid NHS ester
          UV-Tracer Azido-NHS ester
          Azido-PEG4-Acid
          Azido-PEG3-Maleimide
          Azido-Propylamine
          Azido-PEG3-Amine
          Biotin-PEG3-Azide
          TAMRA-Azide-Biotin
          Diazo Biotin-Azide
          Sulfo-link-Biotin-Azide
          Copper-free Click Chemistry產(chǎn)品列表:
          DBCO-PEG4-NHS ester
          DBCO-PEG4-4-Formylbenzoate
          DBCO-Sulfo-NHS ester
          DBCO-NHS ester
          DBCO-Acid

          DBCO-PEG4-Acid
          DBCO-Amine
          DBCO-PEG4-Amine
          DBCO-Maleimide
          DBCO-PEG4-Maleimide
          Fluorescent Probes
          DBCO-Sulfo-link-Biotin
          DBCO-PEG12-Biotin Conjugate
          DBCO-PEG4-Biotin
          Diazo Biotin-DBCO
          DBCO-S-S-PEG3-Biotin

          DBCO-S-S-PEG3-Biotin
          DBCO-PEG4-Phosphoramidite
          DBCO-PEG4-Hydroxyl
          DBCO-PEG4-4-Formylbenzoate
          Tetrazine-DBCO
          DBCO-PEG4-DBCO
          TCO-PEG12-DBCO

           

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