詳細(xì)介紹
1565798-78-8,ACI,DOTA系列螯合劑1,4,7,10-四氮雜環(huán)十二烷-1,4,7,10-四乙酸(DOTA)是一種大環(huán)絡(luò)合劑。通過螯合64銅放射性同位素,它已被用于碳納米管生物結(jié)合物的放射性標(biāo)記。在臨床放射中,DOTA可被N-羥基磺基琥珀酰亞胺激活,與單克隆結(jié)合。
名稱:ACI
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid
10-[2-[[3-[(2-Methyl-1-oxo-2-propen-1-yl)amino]propyl]amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid
CAS:1565798-78-8
化學(xué)式:C23H40N6O8
分子量:528.2908
結(jié)構(gòu)式以及核磁圖譜:
LCMS分析報告:
1565798-78-8,ACI,DOTA系列螯合劑產(chǎn)品簡介:1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent. It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64 Cu radioisotope. DOTA can be activated with N -hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.
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