目錄:MedChemExpress LLC>>生化試劑>> Campesterol | MCE
CAS | 474-62-4 | 純度 | ≥98.0% |
---|---|---|---|
分子量 | 400.68 | 分子式 | C??H??O |
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 5 mg |
貨號 | HY-N1459 | 應用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 474-62-4
產(chǎn)品活性:Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.
研究領(lǐng)域:Metabolic Enzyme/Protease
作用靶點:Endogenous Metabolite
結(jié)構(gòu)分類:甾體類
來源:植物 | 其他科
In Vitro: Campesterol shows a weak cytotoxicity in non-proliferating human umbilical vein endothelial cells (HUVECs). Within the non-cytotoxic concentration range, campesterol significantly inhibits the bFGF-induced proliferation and tube formation of HUVECs in a concentration-dependent manner, while it does not affect the motility of HUVECs. 50 μg/mL of campesterol decreases the cell viability up to about 56% of control(IC50 of over 50 μg/mL).
In Vivo: Campesterol effectively disrupts the bFGF-induced neovascularization in chick chorioallantoic membrane (CAM) in vivo.
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