目錄:MedChemExpress LLC>>信號(hào)通路>> Mivebresib | MedChemExpress
| 參考價(jià) | ￥ 1112 |
| 參考價(jià) | ￥ 1112 |
更新時(shí)間：2023-09-28 14:55:07瀏覽次數(shù)：139評(píng)價(jià)
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| CAS | 1445993-26-9 | 純度 | 99.42% |
|---|---|---|---|
| 分子量 | 459.47 | 分子式 | C??H??F?N?O?S |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號(hào) | HY-100015 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 1445993-26-9
MCE 國(guó)際站：Mivebresib
產(chǎn)品活性：Mivebresib (ABBV-075) 是一種有效的，口服活性的溴結(jié)構(gòu)域和末端結(jié)構(gòu)域 (BET) 抑制劑。Mivebresib 與 BRD4 結(jié)合的 Ki 為 1.5 nM。
研究領(lǐng)域：Epigenetics | Apoptosis
作用靶點(diǎn)：Epigenetic Reader Domain | Apoptosis
In Vitro: Mivebresib inhibit DHT-stimulated transcription of AR target genes without significant effect on AR protein expression. In addition to blocking the transcription activation downstream of AR, Mivebresib is also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins.
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