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          C6830Interferes with Cell Membrane

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          • 上海輔澤商貿(mào)有限公司
          • 2018-08-20 10:13:41
          • 上海市
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          【簡單介紹】

          品牌 Sigma-Aldrich 貨號 C6830
          規(guī)格 Cecropin A ≥97% (HPLC), powder 供貨周期 一周
          Interferes with Cell Membrane Permeability (Ionophores)

          【詳細(xì)說明】

          Interferes with Cell Membrane Permeability (Ionophores)

          Polymyxin B and colistin (polymyxin E) disrupt the cell membrane integrity of Gram-negative bacteria by binding to membrane phospholipids. Eukaryotic cell membranes have phospholipids similar to Gram-negative bacteria, so the polymyxins are most often used clinically as topical antibiotics.

          In contrast, the ionophore antibiotics such as monensin and valinomycin tend to be more active against Gram-positive bacteria, which lack the outer cell membranes. Monensin is an ionophore that forms monovalent ion channels in the cell wall of Gram-positive bacteria and allows the free movement of K+ and Na+ ions along their concentration gradients. Valinomycin is a selective K+ ionophore that triggers mitochondrial transition by facilitating the transport of K+ across the mitochondrial membrane. By altering the intracellular cationic environment of the cell, these agents uncouple mitochondrial oxidative metabolism and inhibit cell growth.

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          100105A mobile ion-carrier that forms stable complexes with divalent cations.
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          407950Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+., Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is a highly specific for divalent cations and more effective than A23187  as a mobile ion carrier for Ca2+.
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          407951null
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          407952Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.
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          407953Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is a 10 mM solution in DMSO. Useful in cell activation experiments when calcium dose-response data are not required., Useful in cell activation experiments when calcium dose-response data are not required. The solid form of this compound is also available.
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          475914Nystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+., A polyene antifungal antibiotic effective against yeast and mycoplasma.
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          481990Nigericin, Sodium Salt, Streptomyces hygroscopicus, CAS 28643-80-3, is an antibiotic K+ ionophore that disrupts the membrane potential and stimulates ATPase activity in mitochondria., Disrupts the membrane potential and stimulates ATPase activity in mitochondria.
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          SRP3013Beta D-4 human recombinant, expressed in E. coli, ≥98% (HPLC), cell culture tested
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          SRP3012Beta D-1 (47 aa) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
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          C6830Cecropin A ≥97% (HPLC), powder
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          C1796Cecropin B ≥97% (HPLC), powder
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          C7927Cecropin P1 Porcine ≥95% (HPLC), powder
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          C4461Colistin sulfate salt 硫酸鹽 ≥15,000 U/mg
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          D2043Defensin HNP-1 human ≥80% (HPLC)
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          D6790Defensin HNP-2 human ≥95% (HPLC)
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          E4632Econazole nitrate salt
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          M7402Magainin II ≥97% (HPLC)
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          SRP3126NP-1 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
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          P0053PGLa
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          03907Tioconazole 97%
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          C6019克霉唑
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          33894克霉唑 VETRANAL, analytical standard
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          P4668吡喹酮 anthelminic, neurogenic
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          46648吡喹酮 VETRANAL, analytical standard
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          P9625吩嗪硫酸甲酯 ≥90% (UV)
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          P1004多粘菌素 B 硫酸鹽
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          H32612-巰基吡啶-N-氧化物 鈉鹽 ≥96%
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          A3281N-(6-氨基己基)-5-氯-1-萘磺酰胺 鹽酸鹽
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          C6143氯己定 二乙酸鹽 水合物 bis(biguanide) antimicrobial
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          C9394氯己定 二葡糖酸鹽 溶液 20% in H2O
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          C9275鈣離子載體 A23187 半鈣鹽 powder
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          21186鈣離子載體 III Selectophore, function tested
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