Tools allowing the growth of cells in a 3-dimensional environment are generally divided into different approaches, including so called scaffold-free and scaffold-based technologies.
3D Scaffolds, traditionally described as tools made of polymeric biomaterials, have the advantage to provide a structural support for cell attachment and tissue development. Scaffolds allow recapitulation of the extracellular environment of cells, the ECM (Extracellular Matrix), by providing attachment sites, the ability for cells to grow in 3D shape, and for some of them, rigidity of this environment and associated soluble factors (growth factors, immune system).
Numerous scaffolds have been developed by innovative companies around the world, and at MilliporeSigma we have chosen to offer a panel of these technologies to the scientific community.

• Simple and efficient cell seeding procedure.
• Cells distributing well in the sponge pores and grow well easily.
• Compatible with well plate and insert.
• Exclusive patent license-Hydrogel-like microporous sponge.
• Appropriate spheroid size with prevented apoptosis in the spheroids center
• Good for cell cryopreservation.
• Form functional spheroids within 24-hours post-seeding and remain stable at least 40 days.