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The Thermo Scientific Acclaim HILIC-10 column is designed for separating highly hydrophilic molecules by hydrophilic interaction liquid chromatography (HILIC). This column is suited for use in a broad range of applications, including separation of hydrophilic drugs and drug metabolites.
Retains highly polar molecules that are not retained by reversed-phase chromatography
Unique selectivity, complementary to reversed-phase columns
Hydrolytically stable
Rugged column packing
Broad application range
The advantage of the Acclaim HILIC-10 phase is the compatibility with up to 20% aqueous phase, while maintaining affinity for polar analytes. Acclaim HILIC-10 columns are available in 3 μm particle size. A variety of column formats are available: 4.6 × 150 mm, for high-throughput routine analysis; 3.0 × 150 mm, for high-throughput analysis with reduced solvent consumption; and 2.1 × 150 mm, for LC-MS analysis.
| Acclaim Mixed-Mode HILIC-1 Columns Specifications | |
|---|---|
| Particle size: | 5 µm |
| Base silica: | Spherical, high-purity |
| Pore size: | 120 Å |
| Surface area: | 300 m2/g |
| Column chemistry: | Proprietary alkyl diol |
| Analytical Columns | |
|---|---|
| Acclaim Mixed-Mode HILIC-1, 3µm Analytical (3.0 x 150mm) | 070090 |
| Acclaim Mixed-Mode HILIC-1, 3µm Analytical (3.0 x 50mm) | 071912 |
| Acclaim Mixed-Mode HILIC-1, 3µm Analytical (2.1 x 150mm) | 070091 |
| Acclaim Mixed-Mode HILIC-1, 5 µm (4.6 x 150 mm) | 066843 |
| Acclaim Mixed-Mode HILIC-1, 5µm (4.6 x 250 mm) | 066844 |
| Acclaim Mixed-Mode HILIC-1, 5 µm (2.1 x 150 mm) | 066847 |
| Guard Columns | |
|---|---|
| Acclaim Mixed-Mode HILIC-1, 5 µm Guard Cartrdiges, (4.6 x 10 mm), 2 ea (use V-2 Holder) | 069706 |
| Acclaim Mixed-Mode HILIC-1, 5µm Guards (3 x 10mm), 2ea, requires holder 069580 | 071913 |
| Acclaim Mixed-Mode HILIC-1, 5µm, Guards (2.1 x 10mm), 2 ea; requires holder 069580 | 069694 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | 074188 |