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          CA IX mouse mAb(12F10)
          • CA IX mouse mAb(12F10)
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          更新時間:2024-08-27 21:00:08

          瀏覽次數(shù):23

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          SourceMouseApplicationsIF
          • Source

            Mouse

          • Applications

            IF,WB,IHC,IP

          • Reactivity

            Human

          • Dilution

            IF: 1:50-200 WB: 1:3000 IP:1:200 IHC 1:50-300

          • Storage

            -20°C/1 year

          • Specificity

            The antibody detects endogenous CA IX proteins.

          • Source/Purification

            The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

          • Immunogen

            Synthetic Peptide of CA IX

          • Uniprot No

            Q16790

          • Alternative names

            CA9; G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1

          • Form

            PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

          • Clonality

            Monoclonal

          • Isotype

            IgG

          • Background

            carbonic anhydrase 9(CA9) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014],

          • Other

            CA9, Carbonic anhydrase 9; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1

          • Mol.Wt (Da)

            49698

          • Concentration

            1 mg/ml

          Product Reactivity Applications Conjugation Catalog Images

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