Maybridge小分子雜環(huán)中間體、醫(yī)藥化學(xué)服務(wù)和篩選化合物庫(kù)

時(shí)間：2024/7/25閱讀：112

Maybridge成立于1962年，是Thermo Fisher Scientific Inc集團(tuán)下專為藥物研發(fā)和生物技術(shù)提供相關(guān)產(chǎn)品和服務(wù)的特殊供應(yīng)商，Maybridge公司47年來(lái)一直致力于為客戶設(shè)計(jì)和提供創(chuàng)新性雜環(huán)中間體，以幫助客戶發(fā)現(xiàn)和設(shè)計(jì)新的有價(jià)值的藥物分子，助力藥物發(fā)現(xiàn)工作。

Maybridge產(chǎn)品包括具有多變化系列的小分子雜環(huán)中間體、醫(yī)藥化學(xué)服務(wù)和篩選化合物庫(kù)。并能在客戶需要時(shí)進(jìn)行適當(dāng)放大生產(chǎn)。

Maybridge篩選化合物庫(kù)

篩選化合物庫(kù)提供超過(guò)56000種不同的藥類分子，并且篩選出靶標(biāo)化合物的幾率很高，大部分都是創(chuàng)新化合物，業(yè)界內(nèi)*具有多樣性的化合物庫(kù)，符合“Lipinski五規(guī)則"，具有較好的性能，含有強(qiáng)效團(tuán)以保證與生物靶點(diǎn)作用。Maybrdige篩選化合物庫(kù)在新藥研發(fā)領(lǐng)域起到關(guān)鍵作用，例如新藥Sorafenib，Olaparib和Sunitinib的開(kāi)發(fā)

2）Maybridge HitFinderTM化合物庫(kù)

篩選化合物庫(kù)的子集HitFinderTM加速了先導(dǎo)化合物的鑒定，提供14400種優(yōu)質(zhì)篩選化合物并提供現(xiàn)貨供應(yīng)，從每個(gè)相似化合物簇中選擇一個(gè)化合物組成HitFinderTM化合物庫(kù)，化合物以干膜狀態(tài)儲(chǔ)存在96或384孔板中，方便客戶使用和儲(chǔ)存，可提供放大生產(chǎn)以滿足先導(dǎo)化合物優(yōu)化的需要。

Maybridge片段庫(kù)

片段庫(kù)提供超過(guò)30000種片段分子和領(lǐng)xian的預(yù)選化合物庫(kù)，加速基于結(jié)構(gòu)的先導(dǎo)化合物的鑒定

1）Maybridge Ro3片段庫(kù)

提供1000種藥類分子，含有強(qiáng)藥效團(tuán)和具有you越的ADME性質(zhì)結(jié)構(gòu)，結(jié)構(gòu)多樣性廣，含有容易結(jié)合的集團(tuán)，靶標(biāo)化合物可快速轉(zhuǎn)變成較大的先導(dǎo)化合物，wan全符合“Rule of Three"，具有較好的性能，保證溶解性（DMSO）。直接使用：客戶定量稱量，化合物儲(chǔ)存在玻璃瓶或多孔板中，并可提供放大生產(chǎn)你滿足先導(dǎo)化合物優(yōu)化的需要。

2）其他的特殊片段庫(kù)包括

Maybridge溴-片段庫(kù)

提供超過(guò)1500中含溴片段的化合物，用于基于X-射線的片段篩選

Maybridge氟-片段庫(kù)

提供超過(guò)5300種含氟片段化合物，用于于19F NMR的片段篩選

Maybridge前體-片段庫(kù)

提供有價(jià)值的活性“前體片段庫(kù)"用于合成片段庫(kù)或開(kāi)發(fā)靶標(biāo)化合物

Maybridge品牌部分產(chǎn)品訂購(gòu)信息：

Casno	貨號(hào)	規(guī)格	品名
2144-37-8	BLT00257EA	10GR	Methyl 5-(chloromethyl)-2-furoate, 95% 甲基 5-(氯甲基)-2-糠酸酯
2144-37-8	BLT00257EB	25GR	Methyl 5-(chloromethyl)-2-furoate, 95% 甲基 5-(氯甲基)-2-糠酸酯
21815-91-8	BTB00300DA	1GR	3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯
21815-91-8	BTB00300EA	10GR	3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯
97051-69-9	BTB00739DA	1GR	N1-[2-Amino-4-(trifluoromethyl)phenyl]acetamide, 97% N1-[2-氨基-4-(三氟甲基)苯基]乙酰胺
13134-76-4	BTB04875EA	10GR	Methyl 3-hydroxybenzo[b]thiophene-2-carboxylate, 97% 甲基 3-羥基苯并[b]噻吩-2-羧酸酯
5819-40-9	BTB05698EA	10GR	4-Bromo-5-methylisoxazol-3-amine, 97% 3-氨基-4-溴-5-甲基異
1889-78-7	DP00542CB	250MG	2-Bromo-1-(4-chlorophenyl)-2-phenylethan-1-one, 95% 2-溴-1--2-苯基乙烷-1-酮
57260-71-6	AW01051ZZ	GR	tert-Butyl tetrahydropyrazine-1(2H)-carboxylate, 97% 1-Boc-
175135-00-9	BTB02778ZZ	GR	4-(2-Chloro-6-nitrophenoxy)benzene-1-sulfonyl chloride, 97%
68337-15-5	AC18635ZZ	GR	4-(1H-1,2,4-Triazol-1-yl)phenol, 97% 4-(1,2,4-三唑基）苯酚
	AC19919ZZ	GR	3-piperidinecarboxylic acid, 97% 六氫yan堿酸
21815-91-8	BTB00300ZZ	GR	3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯
132915-80-1	BTB05127ZZ	GR	3-Chloro-5-(trifluoromethyl)benzene-1,2-diamine, 97% 3-氯-4,5-二氨基三氟甲ben
701-43-9	BTB03706ZZ	GR	3-Chloro-4-fluorobenzamide, 97% 3-氯-4-氟ben甲酰胺
113170-72-2	BTB05134ZZ	GR	3-Bromo-5-(trifluoromethyl)benzene-1,2-diamine, 97% 3-溴-5-三氟甲基-1,2-ben二胺
2973-76-4	BTB06293ZZ	GR	3-Bromo-4-hydroxy-5-methoxybenzaldehyde, 97% 5-溴香蘭素
16789-84-7	BTB03755ZZ	GR	3-Bromo-2-hydroxy-5-nitrobenzaldehyde, 97%
3949-36-8	BTB03234ZZ	GR	3-Acetyl-2H-chromen-2-one, 97% 3-乙?；?/span>香豆su
175135-15-6	BTB05684ZZ	GR	3-[5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl]propan-1-ol, 97%
97051-69-9	BTB00739ZZ	GR	N1-[2-Amino-4-(trifluoromethyl)phenyl]acetamide, 97%
5434-30-0	BTB00549ZZ	GR	N1-(5-Amino-2-methylphenyl)acetamide, 97%
2144-37-8	BLT00257ZZ	GR	Methyl 5-(chloromethyl)-2-furoate, 95%
13134-76-4	BTB04875ZZ	GR	Methyl 3-hydroxybenzo[b]thiophene-2-carboxylate, 97%
14742-32-6	AW01254ZZ	GR	2-Amino-5-phenyl-3-furonitrile, 95%
609-85-8	BTB01924ZZ	GR	2-Amino-3,5-dibromobenzoic acid, 95% 2-氨基-3,5-二溴苯甲酸
175135-09-8	BTB04528ZZ	GR	2,6-Dibromo-3-chloro-4-fluoroaniline, 97% 3-氯-2,6-二溴-4-氟ben胺
21663-61-6	DP01309ZZ	GR	2,5-Dichlorobenzonitrile, 97% 2,5-二氯苯腈
71083-06-2	BTB02003ZZ	GR	Ethyl 8-fluoro-4-hydroxy-3-quinolinecarboxylate, 97%
62482-30-8	BTB00099ZZ	GR	Ethyl 6-bromo-2-methylquinoline-4-carboxylate, 95%
30806-83-8	AC17031ZZ	GR	Ethyl 4-isocyanatobenzoate, 97% 乙基-4-異疊酸苯酯
23795-02-0	BTB00914ZZ	GR	Ethyl 3-(4-hydroxyphenyl)propanoate, 97%
4815-37-6	AW00937ZZ	GR	Ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate, 97%
6193-47-1	AC11174ZZ	GR	Cyclopropyl(2-thienyl)methanone, 97% 環(huán)丙基-2-噻吩基甲酮
175135-07-6	BTB04184ZZ	GR	Benzo[b]thiophene-2-carbohydrazide, 97% 苯并[b]噻吩-2-羧酰肼
145-74-4	BTB06262ZZ	GR	8-Chloronaphthalene-1-sulfonic acid, 97%
175135-22-5	BTB06368ZZ	GR	2-(Propylthio)nicotinic acid, 97%
175135-23-6	BTB06369ZZ	GR	2-(Pentylthio)nicotinic acid, 97%
74470-23-8	BTB06287ZZ	GR	2-(Methylthio)nicotinic acid, 97% 2-(甲硫基)煙酸
40241-78-9	DP01481ZZ	GR	2-(Methylthio)-4,5-dihydro-1H-imidazole hydrobromide, 95%
175135-27-0	BTB06390ZZ	GR	2-(Ethylthio)nicotinamide, 97%
76254-70-1	DP01591ZZ	GR	2-(4-Nitrophenyl)ethanethioamide, 97%
33599-26-7	BTB03301ZZ	GR	2-(4-Chlorophenyl)-2-morpholinoacetonitrile, 97%
5157-08-4	BTB06143ZZ	GR	6-Methyl-2,3,4,5-tetrahydropyridazin-3-one, 97% 4,5-二氫-6-甲基噠嗪-3(2H)-酮
5469-69-2	BTB05877ZZ	GR	6-Chloropyridazin-3-amine, 97% 3-氨基-6-氯代噠嗪
95-24-9	BTB04800ZZ	GR	6-Chloro-1,3-benzothiazol-2-amine, 97% 2-氨基-6-氯苯并噻唑(99%)
4721-98-6	BTB04055ZZ	GR	6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline, 97%
218457-66-0	BTB03829ZZ	GR	6-(4-Chloro-3,5-dimethylphenoxy)pyridin-3-amine, 90%
698-63-5	AC17386ZZ	GR	5-Nitro-2-furaldehyde, 97% 5-硝基糠醛
6537-46-8	BTB03140ZZ	GR	5H-Chromeno[2,3-b]pyridin-5-one, 97% 1-氮雜
436-72-6	BTB04061ZZ	GR	5-Fluoroquinazolin-4-ol, 97%
23602-63-3	BTB03914ZZ	GR	5-Chloro-2-hydroxy-3-methylbenzaldehyde, 95% 5-氯-2-羥基-3-ji甲基ben甲醛
5034-74-2	BTB03758ZZ	GR	5-Bromo-2-hydroxy-3-methoxybenzaldehyde, 97%
465514-39-0	AW01250ZZ	GR	1-[4-(Trifluoromethyl)-2-pyrimidinyl]-4-piperidinecarboxylic acid, 97%
58315-38-1	BTB03244ZZ	GR	1-[2-Nitro-4-(trifluoromethyl)phenyl]piperazine, 97%
219539-29-4	BTB05406ZZ	GR	1-[2-(4-Chlorophenyl)-6H-1,3-thiazin-5-yl]ethan-1-one, 97%
20555-91-3	BTB06155ZZ	GR	1,2-Dichloro-4-iodobenzene, 97% 3,4-二氯碘苯
394-32-1	BTB04130ZZ	GR	1-(5-Fluoro-2-hydroxyphenyl)ethan-1-one, 97% 5-氟-2-羥基苯乙酮
19462-98-7	BTB02521ZZ	GR	5,6-Dichloro-1H-benzo[d]imidazole-2-thiol, 95% 5,6-二氯苯咪唑-2-硫
852180-39-3	AW01246ZZ	GR	5-(3-Pyridinyloxy)-2-furoic acid, 97%
2359-60-6	BTB05830ZZ	GR	4-Piperidinoaniline, 97% 4-(1-哌啶基)苯胺
38869-37-3	AC10033ZZ	GR	4-Piperazinophenol dihydrobromide, 97%
3967-01-9	BTB00610ZZ	GR	4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 97%
306934-78-1	AW01194ZZ	GR	4-Chloro-5-methyl-6-phenylthieno[2,3-d]pyrimidine, 97%
140675-42-9	BTB04131ZZ	GR	1-(3,5-Difluoro-2-hydroxyphenyl)ethan-1-one, 97%
175135-14-5	BTB05258ZZ	GR	4-Bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole, 97%
5819-40-9	BTB05698ZZ	GR	4-Bromo-5-methylisoxazol-3-amine, 97% 3-氨基-4-溴-5-甲基異
62054-72-2	BTB01843ZZ	GR	4-[2-Nitro-4-(trifluoromethyl)phenyl]morpholine, 97%
306934-75-8	AW01128ZZ	GR	4-[(2-Chloro-6-fluorobenzyl)oxy]-3-methoxybenzaldehyde, 97%
932-22-9	BTB06282ZZ	GR	4,5-Dichloro-3-pyridazinol, 95% 4,5-二氯噠嗪-3(2H)-酮
440-60-8	AC18836ZZ	GR	(2,3,4,5,6-Pentafluorophenyl)methanol, 97% 五氟芐醇
175135-06-5	BTB03983ZZ	GR	3,5-Dichloro-4-(2-chloro-4-nitrophenoxy)benzene-1-sulfonyl chloride, 97%
90-59-5	BTB02697ZZ	GR	3,5-Dibromo-2-hydroxybenzaldehyde, 95% 3,5-二溴水yang醛
725-89-3	DP01857ZZ	GR	3,5-Di(trifluoromethyl)benzoic acid, 97% 3,5-雙(三氟甲基)苯甲酸
3430-40-8	BTB03853ZZ	GR	2-Piperidinobenzamide, 97%
39643-31-7	BTB02217ZZ	GR	2-Piperidinoaniline, 97% 2-(1-哌啶基)ben胺
5585-33-1	BTB02219ZZ	GR	2-Morpholinoaniline, 97% 4-2-胺苯基嗎啉
613-30-9	BTB06234ZZ	GR	2-Methyl-6-nitroquinoline, 97% 2-甲基-6-硝基喹lin
113170-71-1	BTB04900ZZ	GR	2-Bromo-6-nitro-4-(trifluoromethyl)aniline, 97%
1889-78-7	DP00542ZZ	GR	2-Bromo-1-(4-chlorophenyl)-2-phenylethan-1-one, 95%
205178-80-9	BTB02944ZZ	GR	2-Bromo-1-(4-chloro-3-methylphenyl)ethan-1-one, 97%

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Maybridge小分子雜環(huán)中間體、醫(yī)藥化學(xué)服務(wù)和篩選化合物庫(kù)

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